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Phenotype Image Detail
Image
Caption Electron micrographs of bladder smooth muscle cells. The overall morphology of the smooth muscle cells are very similar, however the number of thick filaments in a given field is greatly reduced in Myh11tm2Peri/Myh11tm2Peri (SM2-/-) mice. (Top) Longitudinal section showing morphology of smooth muscle cells (Magnification 6,000x). (Middle) Cross-section of myosin filaments (Magnification 68,000x). (Bottom) Enlarged images (25x) of square areas indicated in Middle.) Arrows point to the myosin thick filaments; circles indicate the locations of dense bodies.
Copyright This image is from Chi M, Proc Natl Acad Sci U S A 2008 Nov 25;105(47):18614-8. Copyright 2008 National Academy of Sciences, U.S.A. J:142230
Associated
Alleles
Symbol Name
Myh11tm2Peri myosin, heavy polypeptide 11, smooth muscle; targeted mutation 2, Muthu Periasamy
Associated
Genotypes
Allelic Composition Genetic Background
Myh11tm2Peri/Myh11tm2Peri involves: 129 * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory