Phenotype Image Detail

Image

Caption

(A) Stages of cataract development. From left to right: 1.5 old Nrcam^tm1Fgr/Nrcam⁺ (NrCAM ^+/-) lens; Nrcam^tm1Fgr/Nrcam^tm1Fgr (NrCAM^-/-) littermate; both lenses from a 4 month old mutant mouse; 9 month old mutant lens; same magnification as in b. (B) Lens pairs from 11 month old mutant siblings. (C) Eye of a freshly euthanized mutant mouse. (D) Weights of heterozygous and mutant littermates during postnatal development. Black line and symbols, heterozygous mice; light line and symbols, mutant mice. (E) Rotarod test. The number of time the mice fell from the rod in 3 minutes is indicated for a nonmioving rod and the rod rotating with 6.5 rpm. Each mouse was confronted without prior rod experience, first with the nonmoving rod, and after a recovery time, with the rotating rod.

Copyright

This image is from More MI, J Cell Biol 2001 Jul 9;154(1):187-96, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:70385

Associated Alleles

Symbol	Name
Nrcam^tm1Fgr	neuronal cell adhesion molecule; targeted mutation 1, Fritz G Rathjen