Gene Expression Image Detail

Reference

Figure

ID

J:138310 Xu C, et al., Gene Expr Patterns. 2008 Sep;8(7-8):502-7

1

MGI:3845164

Image

Caption

A schema of sagittal plate of the mouse brain is shown in (A1); coronal planes of brains made through the red line are shown in A2 (E12.5), A3 (E13.5), A4 (E14.5) and A5 (E15.5). In (A2-A5), the red rectangles indicate regions of focus; expression domain of Sim1 is in blue; OB, olfactory bulb; NC, neocortex; TL, thalamus; AD, amygdale; HP, hypothalamus; v3, third ventricle; OT, optic tract; SC, spinal cord; the purple arrows indicate the orientation of hypothalamic paraventricular nucleus (PVN) and supraoptic nucleus (SON) neuronal migration route in the E14.5 and E15.5 brain. Coronal sections. Selective higher power images of each gene are shown in column 5; positions of these images are indicated by green rectangles of selected lower magnification images. The white dashed lines demarcate the PVN/SON progenitors at E12.5 and E13.5; and the PVNs (triangular shape) and SONs (slanted rod shape) at E14.5 and E15.5. The white/grey dashed lines in (C-F) are drawn according to the Sim1 expression region in corresponding adjacent sections (not shown). Scale bars, 70 microns in E12.5; 75 microns in E13.5; 80 microns in E14.5; 90 microns in E15.5; 15 microns in B5, C5, D5, E5, F5.

Copyright

Reprinted with permission from Elsevier from doi:10.1016/j.gep.2008.06.003 Gene Expr Patterns 8: 502-7, Xu C; Fan CM, Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei. Copyright 2008

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
_B1	MGI:3845281 (Sim1)
_B2	MGI:3845281 (Sim1)
_B3	MGI:3845281 (Sim1)
_B4	MGI:3845281 (Sim1)
_B5	MGI:3845281 (Sim1)
_C1	MGI:3845285 (Robo3)
_C2	MGI:3845285 (Robo3)
_C3	MGI:3845285 (Robo3)
_C4	MGI:3845285 (Robo3)
_C5	MGI:3845285 (Robo3)
_D1	MGI:3845292 (Plxna1)
_D2	MGI:3845292 (Plxna1)
_D3	MGI:3845292 (Plxna1)
_D4	MGI:3845292 (Plxna1)
_D5	MGI:3845292 (Plxna1)
_E1	MGI:3845293 (Plxna4)
_E2	MGI:3845293 (Plxna4)
_E3	MGI:3845293 (Plxna4)
_E4	MGI:3845293 (Plxna4)
_E5	MGI:3845293 (Plxna4)
_F1	MGI:3845295 (Plxnb1)
_F2	MGI:3845295 (Plxnb1)
_F3	MGI:3845295 (Plxnb1)
_F4	MGI:3845295 (Plxnb1)
_F5	MGI:3845295 (Plxnb1)