Gene Expression Image Detail

Reference

Figure

ID

J:143398 Homma S, et al., Gene Expr Patterns. 2009 Jan;9(1):1-26

4

MGI:3829793

Image

Caption

Whole-mount in situ hybridization (A-C), or tissue sections (D-P). (A-C) Lateral views of E10 embryos. NGL1, NGL2, and NGL3expression is shown in A-C, respectively. te, telencephalon; di, diencephalon; me, mesencephalon; rh, rhombencephalon; sc, spinal cord; eye, optic cup; ot, otocyst; ba,branchial arch; he, heart; and lb, limb bud. (D-F) Three adjacent transverse sections of the telencephalon (te), showing NGL1, NGL2, and NGL3 expression in D-F,respectively. In D, arrowheads indicate NGL1 expression in apparent post-mitotic cells, eye, and optic cup. (G) A transverse section through the telencephalon, showinghigh levels expression of NGL3 in dorsal regions, whereas low levels of expression are in ventral regions. (H) NGL3 expression in a horizontal section through the mesencephalon (me), trigeminal ganglia (Vth), and optic cup (eye). (I) NGL3 expression in a transverse section through the rhombencephalon. The fourth ventricle (4thv); VIIIth, cochlear ganglia; hv, primary head vein; and ot, otocyst. (J) NGL2 expression in a transverse section through the rhombencephalon (rh) and otocyst (ot). (K) A frontal section through the branchial arches (ba), showing NGL2 expression in the endodermal lining (arrowheads). (L) NGL3 expression in a frontal section through the branchial arches (ba). (M) NGL1 expression in a transverse section of the spinal cord. Arrowheads indicate expression in the ventral horn. (N) A transverse section of the spinal cord, showing NGL2 hybridization in the dorsal (d) and ventral (v) domains. The small intermediate region (i) between them is devoid of NGL2 expression. (O) NGL3 expression in apparent neurons (arrowheads) in a transverse section through the brachial spinal cord. sy, sympathetic trunk. (P) NGL3 expression in the atrial wall of the heart (arrowheads). (Q) Summary of NGL expression in a schematic drawing of an obliquely parasagittal plane of E10 mouse embryo. Orange dots, NGL1 expression; green dots, NGL2 expression; and blue dots, NGL3 expression. The approximate levels and orientations of the sections are shown by thick lines with corresponding alphabets.

Copyright

Reprinted with permission from Elsevier from doi:10.1016/j.gep.2008.09.004 Gene Expr Patterns 9: 1-26, Homma S; Shimada T; Hikake T; Yaginuma H, Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo. Copyright 2009

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:3830074 (Lrrc4c)
B	MGI:3830075 (Lrrc4)
C	MGI:3830076 (Lrrc4b)
D	MGI:3830074 (Lrrc4c)
E	MGI:3830075 (Lrrc4)
F	MGI:3830076 (Lrrc4b)
G	MGI:3830076 (Lrrc4b)
H	MGI:3830076 (Lrrc4b)
I	MGI:3830076 (Lrrc4b)
J	MGI:3830075 (Lrrc4)
K	MGI:3830075 (Lrrc4)
L	MGI:3830076 (Lrrc4b)
M	MGI:3830074 (Lrrc4c)
N	MGI:3830075 (Lrrc4)
O	MGI:3830076 (Lrrc4b)
P	MGI:3830076 (Lrrc4b)