Phenotype Image Detail

Image

Caption

Hematoxylin and eosin stained sections of the gastrocnemius (A), triceps brachii (B), paraspinal (C), and quadriceps (D) muscles of six month old Col15a1^tm1Pih/Col15a1^tm1Pih mice showing cell degeneration (curved arrows, A and C) with macrophage infiltration (A), regenerative fibers (thin arrow, B) central nuclei (thin arrow, C) and increased variation in fiber size with atrophic muscle fibers (D, arrowheads) compared with age-matched wild-type mice (E). Original magnifications: A and D, x300; B, x200; C and E, x80.

Copyright

This image is from Eklund L, Proc Natl Acad Sci U S A 2001 Jan 30;98(3):1194-9. Copyright 2001 National Academy of Sciences, U.S.A. J:67212

Associated Alleles

Symbol	Name
Col15a1^tm1Pih	collagen, type XV, alpha 1; targeted mutation 1, Taina Pihlajaniemi

Associated Genotypes

Allelic Composition	Genetic Background
Col15a1^tm1Pih/Col15a1^tm1Pih	involves: 129S1/Sv * 129X1/SvJ