Phenotype Image Detail

Image

Caption

Histological analysis of wild-type (+/+), Fgf23^tm1Tyam/Fgf23⁺ (+/-) and Fgf23^tm1Tyam/Fgf23^tm1Tyam (-/-) bone. A: Soft X-rays of femurs prepared from 7 week old mice. B and C: Villanueva-Goldner stain of undecalcified femurs prepared from 2 and 7 week old mice. B: Distal metaphysis of femurs isolated at 2 weeks (upper) and 7 weeks (lower) of age. Original magnification, x4. C: Growth plates of femurs at 2 weeks (upper) and 7 weeks (lower) of age. Mineralized bone tissues are colored in green, and unmineralized osteoid tissues are shown in orange. Original magnification, x20.

Copyright

This image is from Shimada T, J Clin Invest 2004 Feb;113(4):561-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:88172

Associated Alleles

Symbol	Name
Fgf23^tm1Tyam	fibroblast growth factor 23; targeted mutation 1, Takeyoshi Yamashita

Associated Genotypes

Allelic Composition	Genetic Background
Fgf23^tm1Tyam/Fgf23^tm1Tyam	involves: C57BL/6 * CBA