Phenotype Image Detail

Image

Caption

In the Med1^tm1Jkr/Med1^tm1Jkr (PBP-/-) embryos, paucity of retinal pigment (arrows, B,D and F) and defective lens formation (D) is evident. In wild-type (WT) embryos, retinal pigment (arrows, A,C and E) and the lining epithelium of the lens are well developed (C). Sections C-F were stained with hematoxylin and eosin

Copyright

This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328

Associated Alleles

Symbol	Name
Med1^tm1Jkr	mediator complex subunit 1; targeted mutation 1, Janardan K Reddy

Associated Genotypes

Allelic Composition	Genetic Background
Med1^tm1Jkr/Med1^tm1Jkr	involves: 129P2/OlaHsd * C57BL/6