About   Help   FAQ
Phenotype Image Detail
Image
Caption Electron microscopic analysis of diaphragm in Atp2a1tm1Dhm/Atp2a1tm1Dhm newborn mice. A: Longitudinally oriented diaphragm muscle demonstrating a region of normal myofiber alignment immediately adjacent to a region of hypercontraction. In the regions of hypercontraction, the distance between Z-bands was ~1.3 um compared with about 2 um in the normally contracted regions. Note the prominence of the Z-bands within the regions of hypercontraction. B: An enlargement of a longitudinally oriented myofiber with marked hypercontraction, prominent Z-bands, complete overlap of thick and thin filaments, and intrusion of filaments into the Z-band region.
Copyright This image is from Pan Y, J Biol Chem 2003 Apr 11;278(15):13367-75 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:82947
Associated
Alleles
Symbol Name
Atp2a1tm1Dhm ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; targeted mutation 1, David H MacLennon
Associated
Genotypes
Allelic Composition Genetic Background
Atp2a1tm1Dhm/Atp2a1tm1Dhm involves: CD-1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory