Phenotype Image Detail

Image

Caption

Light microscopy of mineralized thin sections through mandibular molars from 16 week wild-type and Amelx^tm1Kul/Amelx^tm1Kul mice. A: Wild-type dentition shows a normal and relatively even enamel layer over the tooth crown. B: Detentition from the Amelx^tm1Kul/Amelx^tm1Kul mouse has a markedly reduced enamel thickness. Paired arrowheads indicate thickness of the enamel layer.

Copyright

This image is from Gibson CW, J Biol Chem 2001 Aug 24;276(34):31871-5 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:71126

Associated Alleles

Symbol	Name
Amelx^tm1Kul	amelogenin, X-linked; targeted mutation 1, Ashok B Kulkarni

Associated Genotypes

Allelic Composition	Genetic Background
Amelx^tm1Kul/Amelx^tm1Kul	involves: 129S1/Sv * 129X1/SvJ * C57BL/6