Phenotype Image Detail

Image

Caption

Histological analysis of skeletal muscle fibers from Cav3^tm1Mls/Cav3^tm1Mls. Muscle tissue sections from wild-type (WT) mice (upper panel) and Cav3^tm1Mls/Cav3^tm1Mls (Cav-3 KO, lower panel) mice, were stained with hematoxylin and eosin (H&E). Note that muscle tissue sections from mutant mice exhibit variability in muscle fiber size and reveal the presence of some necrotic fibers (arrows).

Copyright

This image is from Galbiati F, J Biol Chem 2001 Jun 15;276(24):21425-33 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:69965

Associated Alleles

Symbol	Name
Cav3^tm1Mls	caveolin 3; targeted mutation 1, Michael P Lisanti

Associated Genotypes

Allelic Composition	Genetic Background
Cav3^tm1Mls/Cav3^tm1Mls	involves: 129/Sv * C57BL/6J * SJL
Cav3^tm1Mls/Cav3^tm1Mls	FVB.Cg-Cav3^tm1Mls