Phenotype Image Detail

Image

Caption

Barrier-dependent dye exclusion assay in Prss8^tm1.2Hum/Prss8^tm1.1Hum Tg(KRT14-cre)1Ipc/0 (left; n=8) and control (right, n=5) pups. Representative photograph revealing dye penetration of all epidermal surfaces, especially ventrally in mutant, but not in control pups.

Copyright

This image is from Leyvraz C, J Cell Biol 2005 Aug 1;170(3):487-96, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:100139

Associated Alleles

Symbol	Name
Prss8^tm1.1Hum	serine protease 8 (prostasin); targeted mutation 1.1, Edith Hummler
Prss8^tm1.2Hum	serine protease 8 (prostasin); targeted mutation 1.2, Edith Hummler
Tg(KRT14-cre)1Ipc	transgene insertion 1, I Pierre Chambon

Associated Genotypes

Allelic Composition	Genetic Background
Prss8^tm1.1Hum/Prss8^tm1.2Hum Tg(KRT14-cre)1Ipc/0	involves: 129/Sv * C57BL/6 * FVB/N * SJL