Phenotype Image Detail

Image

Caption

A: Hematoxylin and eosin stained cross-sections of hearts from 3 month old wild type (B⁺/B⁺) and Myh10^{tm6(Myh9/GFP)Rsad}/Myh10^{tm6(Myh9/GFP)Rsad} (B^a*/B^a*) mice. Scale bar, 1.3 mm. Wild type (C and E) and mutant (D and F) heart sections were stained with hematoxylin and eosin (C and D) or Alexa Fluor 594-conjugated wheat germ agglutinin to visualize the cell membrane (E and F). The blue in E and F is 4'6'-diamidino-2-phenylindole staining of nuclei. Scale bars: D, 50 um; F, 20 um. Rv, right ventricle; LV, left ventricle.

Copyright

This image is from Bao J, J Biol Chem 2007 Jul 27;282(30):22102-11 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:124610

Associated Alleles

Symbol	Name
Myh10^tm6(Myh9/GFP)Rsad	myosin, heavy polypeptide 10, non-muscle; targeted mutation 6, Robert S Adelstein

Associated Genotypes

Allelic Composition	Genetic Background
Myh10^tm6(Myh9/GFP)Rsad/Myh10^tm6(Myh9/GFP)Rsad	involves: 129S6/SvEvTac * C57BL/6