Phenotype Image Detail

Image

Caption

A-D: Incisors of 3 week old (A and B) and 12 month old (C and D) Sp6^tm1Yoya/Sp6⁺ (+/-, A and C) and Sp6^tm1Yoya/Sp6^tm1Yoya (-/-, B and D) mice. B: Incisor development of 3 week old homozygous mice is delayed. D: 12 month old homozygous mice had an excess number of incisors with a mineral defect. E-H: Radiogram analysis of 6 month old mouse heads from heterozygous (E and F, enlarged) and homozygous mice (G and H, enlarged). asterisk, molars; in, incisors; arrowheads, al, alveolar bones (arrowheads); rt, roots.

Copyright

This image is from Nakamura T, J Biol Chem 2008 Feb 22;283(8):4825-33 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:132157

Associated Alleles

Symbol	Name
Sp6^tm1Yoya	trans-acting transcription factor 6; targeted mutation 1, Yoshihiko Yamada

Associated Genotypes

Allelic Composition	Genetic Background
Sp6^tm1Yoya/Sp6^tm1Yoya	B6.129-Sp6^tm1Yoya