Phenotype Image Detail

Image

Caption

Placenta stage E14.5 was analyzed in wild type, Gab1^tm3Wbm/Gab1^tm3Wbm (deltaGrb2/deltaGrb2), Gab1^tm2Wbm/Gab1^tm2Wbm (deltaMet/deltaMet), and Gab1^tm2WbmGab1^tm3Wbm (deltaGrb2/deltaMet) mice. There is no rescue of the thin labyrinth layer phenotype in Gab1^tm2WbmGab1^tm3Wbm mice (d) Scale bar: A-H, 0.5mm. Liver-to-body-weight ratios of different Gab1 knockin embryos were determined at E14.5 (I).

Copyright

This image is from Schaeper U, Proc Natl Acad Sci U S A 2007 Sep 25;104(39):15376-81. Copyright 2007 National Academy of Sciences, U.S.A. J:125303

Associated Alleles

Symbol	Name
Gab1^tm2Wbm	growth factor receptor bound protein 2-associated protein 1; targeted mutation 2, Walter Birchmeier
Gab1^tm3Wbm	growth factor receptor bound protein 2-associated protein 1; targeted mutation 3, Walter Birchmeier

Associated Genotypes

Allelic Composition	Genetic Background
Gab1^tm3Wbm/Gab1^tm3Wbm	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1
Gab1^tm2Wbm/Gab1^tm3Wbm	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1
Gab1^tm2Wbm/Gab1^tm2Wbm	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1