Phenotype Image Detail

Image

Caption

Electron micrograph of the stria vascularis (A,B) and the organ of Corti of the cochleae from Ednrb^WS4/Ednrb^WS4 mice at 3 weeks (A,C) or wild type (B). A: While marginal cells (MC) and basal cells (BC) are visible in the stria, no intermediate cells are discernible. In this particular cochlea, Reissner membrane (RM) is attached to stria vascularis owing to complete endolymphatic collapse. SC; spriral ligament cell. B: Intermediate cells (I) are visible between marginal cells (MC) and basal cells (BC). C: Reissner membrane (RM) is attached to organ of Corti, so that no endolymphatic space is left. While pillar cells (PC) are fairly well preserved, outer hair cells (OHC) and inner hair cells (IHC) are degenerated. BM: basilar membrane. Scale bars: 5um

Copyright

This image is from Matsushima Y, Mamm Genome 2002 Jan;13(1):30-5 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:76584

Associated Alleles

Symbol	Name
Ednrb^WS4	endothelin receptor type B; Waardenburg syndrome 4

Associated Genotypes

Allelic Composition	Genetic Background
Ednrb^WS4/Ednrb^WS4	involves: BALB/c * MSM