Phenotype Image Detail

Image

Caption

Trichrome-stained sections of representative liver samples of wild type (A) and Mat1a^tm1Jmm/Mat1a^tm1Jmm mice (B) fed a choline deficient (CD) diet for 6 days. Minimal steatosis or no change was seen in the livers of the wild type littermates (A), whereas severe macrovesicular steatosis was observed in more than 75% of hepatocytes in the homozygous mice (B). Magnification x100

Copyright

This image is from Lu SC, Proc Natl Acad Sci U S A 2001 May 8;98(10):5560-5. Copyright 2001 National Academy of Sciences, U.S.A. J:69408

Associated Alleles

Symbol	Name
Mat1a^tm1Jmm	methionine adenosyltransferase 1A; targeted mutation 1, Jose M Mato

Associated Genotypes

Allelic Composition	Genetic Background
Mat1a^tm1Jmm/Mat1a^tm1Jmm	involves: 129/Sv * C57BL/6