Phenotype Image Detail

Image

Caption

A: Wild type aorta composed of intima and media (arrow) and adventitia (arrowheads). There are blood cells (star) in the lumen. B: High magnification of wild type aorta. Elastic fiber (large arrows) and smooth muscle cells (small arrows) of the intima can be seen. C: A dissecting aneurysm of Col3a1^tm1Jae/Col3a1^tm1Jae mouse aorta. The intima and media (arrow) were ruptured and blood (star) filled in between media and adventitia (arrowheads). D: High magnification of mutant mouse aorta. Scale bar: A & C: 100um; B & D: 25um

Copyright

This image is from Liu X, Proc Natl Acad Sci U S A 1997 Mar 4;94(5):1852-6 SS 18 /C?. Copyright 1997 National Academy of Sciences, U.S.A. J:39273

Associated Alleles

Symbol	Name
Col3a1^tm1Jae	collagen, type III, alpha 1; targeted mutation 1, Rudolf Jaenisch

Associated Genotypes

Allelic Composition	Genetic Background
Col3a1^tm1Jae/Col3a1^tm1Jae	involves: 129S4/SvJae