Phenotype Image Detail

Image

Caption

A & B: Dorsal views of the left forefeet of 15.5dpc wild-type (A) and Hoxd11^tm1Ipc/Hoxd11^tm1Ipc (B) fetuses stained with alcian blue. The mutant lunate blastema is thicker than the wild-type. C & D: Dorsal views of 3 day old wild-type (C) and mutant (D) mice left forefeet. The enlarged lunate portion of the SL strongly alters the overall aspect of the mutant first carpal row. I-V, digit number; L, lunate part of the SL; M, metacarpal; P1, P2, P3, phalanges; S, scaphoid part of the SL

Copyright

This image is from Favier B, Proc Natl Acad Sci U S A 1995 Jan 3;92(1):310-4. Copyright 1995 National Academy of Sciences, U.S.A. J:22289

Associated Alleles

Symbol	Name
Hoxd11^tm1Ipc	homeobox D11; targeted mutation 1, Pierre Chambon

Associated Genotypes

Allelic Composition	Genetic Background
Hoxd11^tm1Ipc/Hoxd11^tm1Ipc	either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)