Phenotype Image Detail

Image

Caption

B & C: Comparison of hematoxylin and eosin stained sections of liver from wild-type and Neil1^tm1Rsld/Neil1^tm1Rsld male mice, respectively. Micro- and macrovesicular steatosis of centrilobular hepatocytes is prominent in the mutant mouse. D: Oil red O staining of sections of flash-frozen liver from the mutant male mouse. EL Hematoxylin and eosin stained kidney section from an obese mutant mouse showing vacuoles in proximal epithelial cells.

Copyright

This image is from Vartanian V, Proc Natl Acad Sci U S A 2006 Feb 7;103(6):1864-9. Copyright 2006 National Academy of Sciences, U.S.A. J:106077

Associated Alleles

Symbol	Name
Neil1^tm1Rsld	nei endonuclease VIII-like 1 (E. coli); targeted mutation 1, R Stephen Lloyd

Associated Genotypes

Allelic Composition	Genetic Background
Neil1^tm1Rsld/Neil1^tm1Rsld	involves: 129S1/Sv * C57BL/6