Phenotype Image Detail

Image

Caption

A: Alizarin red- and Alcian blue-stained skeletons from a P30 control (upper) and Sumf1^{Gt(RST760)Byg}/Sumf1^{Gt(RST760)Byg} (lower) mouse. Growth retardation, spinal kyphosis, reduced length of long bones, and skull deformities are evident in the homozygous mouse. B: Facitron radiography of a P30 control mouse (left) and a homozygous mutant littermate (right) shows that the homozygous skull is significantly shorter. C: Loss of spinous process of dorsal vertebrae in P30 homozygous mice (right) compared with control (left). D: Analysis of distal tibia shows enlarged epiphysis and metaphysis in homozygous mice (right) compared with control (left).

Copyright

This image is from Settembre C, Proc Natl Acad Sci U S A 2007 Mar 13;104(11):4506-11. Copyright 2007 National Academy of Sciences, U.S.A. J:120146

Associated Alleles

Symbol	Name
Sumf1^Gt(RST760)Byg	sulfatase modifying factor 1; gene trap RST760, BayGenomics

Associated Genotypes

Allelic Composition	Genetic Background
Sumf1^Gt(RST760)Byg/Sumf1^Gt(RST760)Byg	involves: 129P2/OlaHsd * C57BL/6