Phenotype Image Detail

Image

Caption

Immunohistochemical analysis of lymph nodes and lymphoid aggregates of the gut of wild-type and Pten^tm1Rps/Pten⁺ mice. CD3-positive cells appear brown and B220-positive cells appear blue. Arrows point to the lumen side of the intestinal wall. Arrowheads point to the germinal centers. (d and e) Lymph node of wild-type mouse (d) and Pten^tm1Rps/Pten⁺ mouse (e). (f and g) Colonic lymphoid aggregates of the wild-type mouse (f) and the heterozygous mouse (g).

Copyright

This image is from Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8. Copyright 1999 National Academy of Sciences, U.S.A. J:53065

Associated Alleles

Symbol	Name
Pten^tm1Rps	phosphatase and tensin homolog; targeted mutation 1, Ramon Parsons

Associated Genotypes

Allelic Composition	Genetic Background
Pten^tm1Rps/Pten^+	involves: 129S1/Sv * C57BL/6J