Phenotype Image Detail

Image

Caption

Transmission electron microscopic images of cells in Henle's layer of the IRS in Krt71^Mhdarco12/⁺ or Krt71^Mhdarco12/Krt71^Mhdarco12 mice on postnatal day 13. Aggregates are formed in the homozygous or heterozygous mutant's Henle layer that is composed of intermediate filaments that form a whorl. Linear portions of intermediate filaments are found only at the periphery of aggregates (b), in the vicinity of desmonsomes (black arrow in b) and associated with trichohyalin granula (white arrow in a). Abbreviations: Aggregates (Ag) trichohyalin granula (T). Scalebar 0.2um

This image is from Runkel F, Mamm Genome 2006 Dec;17(12):1172-82 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:116206

Associated
Alleles

Symbol	Name
Krt71^Mhdarco12	keratin 71; Martin Hrabe de Angelis reduced coat 12

Associated
Genotypes

Allelic Composition	Genetic Background
Krt71^Mhdarco12/Krt71^Mhdarco12	C3HeB/FeJ-Krt71^Mhdarco12
Krt71^Mhdarco12/Krt71⁺	C3HeB/FeJ-Krt71^Mhdarco12

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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