Gene Expression Image Detail

Reference

Figure

ID

J:118937 Kaji K, et al., Development. 2007 Mar;134(6):1123-32

3

MGI:3703550

Image

Caption

(A) Wild-type (top panels) and homozygous null(bottom panels) embryos at 5.5 dpc were stained for Oct4 (green) and alpha7-integrin (red). (B) Whole-mount in situ hybridisation of heterozygous (top) and homozygous null (bottom) embryos at 5.5 dpc for Cdx2 (left-hand panels), and Mash2 (right-hand panels). (C) Heterozygous (top panels) and homozygous null (bottom panels) embryos at 5.5 dpc were stained for Gata4 (red) and Oct4 (green). A close-up of the homozygous null embryo is shown in the inset at the bottom of each panel to illustrate co-expression of Oct4 and Gata4 in a subset of cells (arrow), in addition to Oct4 or Gata4 single-positive cells (asterisk and arrowhead, respectively).

Copyright

This image is from Kaji K, Development 2007 Mar;134(6):1123-32 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A Oct4 +/+	MGI:3703637 (Pou5f1)
A alpha7-inegrin +/+	MGI:3703713 (Itga7)
A Oct4 -/-	MGI:3703637 (Pou5f1)
A alpha7-integrin -/-	MGI:3703713 (Itga7)
B Cdx2 +/-	MGI:3703711 (Cdx2)
B Mash2 +/-	MGI:3703712 (Ascl2)
B Cdx2 -/-	MGI:3703711 (Cdx2)
B Mash2 -/-	MGI:3703712 (Ascl2)
C Oct4 +/-	MGI:3703637 (Pou5f1)
C Gata4 +/-	MGI:3703639 (Gata4)
C Oct4 -/-	MGI:3703637 (Pou5f1)
C Gata4 -/-	MGI:3703639 (Gata4)
C merge +/-	MGI:3703639 (Gata4) MGI:3703637 (Pou5f1)
C merge -/-	MGI:3703639 (Gata4) MGI:3703637 (Pou5f1)
A merge +/+	MGI:3703637 (Pou5f1)
A merge -/-	MGI:3703637 (Pou5f1)