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Gene Expression Image Detail
Reference
Figure
ID
J:31212 Shimamura K, et al., Development. 1995 Dec;121(12):3923-33
3
MGI:1934585
Image
Caption A-C Dorsorostral views of neural plate stage embryos. D- F lateral views of neurulation stage embryos. G and H mid-sagittal views of the brain at 10.0 and 11.5 dpc, respectivly. I - K transverse sections at 11.5 dpc. A, anterior is at the bottom. B, arrowhead points to the midline. C, arrowhead points to a narrow loop in the floor of the neural groove. D, arrows point to separate domains of expression in the forebrain, midbrain/posterior diencephalon, hindbrain, and anterior spinal cord. F - G, simultaneous detection of Nkx2.2 (brown in F, purple in G,H) and Shh (purple in F, brown in G, H). G and H, large arrows point to the midline just ventral to the optic stalk. F, asteriks is prosencephalon. G, H, large arrowheads point to zona limitans, G, small arrowheads interrhombomeric boundaries. G, open arrow is the rostral limit of Shh expression at the ventral midline. G,H small arrows point to the medial ganglionic eminence. I-J the planes of the sections are indicated in G. K is a transverse section of the spinal cord and hindbrain at the level of cervical flexure. Labels: di, diencephalon; dt, dorsal thalamus; f, forebrain; fp, floor plate; h, hindbrain; he, heart; hf, neural plate; hp, head process; is, isthmus; m, midbrain; ma, mammillary area; me, mesencephalon; mge, medial ganglionic eminence; n, notochord; oc, optic cup; os,optic stalk; pos, postotic sulcus; pt, pretectum; r2/r3,rhombomere 2/3 boundary; rh, rhombencephalon; rt, Rathke's pouch; sc, spinal cord; sp, secondary prosencephalon; t, telencephalic vesicle; tb, tailbud; tu, tubural hypothalamus; vt, ventral thalamus; zl, zona limitans. Scale bars, 200 microns for A - H and 100 microns for I- K.
This image is from Shimamura et al., Development 121: 3923-3933 (1995), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.
Associated
Assays
Label Assay & Result Details (Gene Symbol) Spatial Mapping
A MGI:1934636 (Nkx2-2)
B MGI:1934636 (Nkx2-2)
C MGI:1934638 (Shh)
D MGI:1934636 (Nkx2-2)
E MGI:1934638 (Shh)
F MGI:5694138 (Nkx2-2) MGI:5694139 (Shh)
G MGI:1934636 (Nkx2-2) MGI:1934638 (Shh) EMAGE:3281
H MGI:1934636 (Nkx2-2) MGI:1934638 (Shh)
I MGI:1934636 (Nkx2-2) MGI:1934638 (Shh) EMAGE:3281
J MGI:1934636 (Nkx2-2) MGI:1934638 (Shh) EMAGE:3281
K MGI:1934636 (Nkx2-2) MGI:1934638 (Shh) EMAGE:3281

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory