Gene Expression Image Detail

Reference

Figure

ID

J:41878 Zoltewicz JS, et al., Development. 1999 Nov;126(22):5085-95

5

MGI:1346352

Image

Caption

A dorsal view of the lower jaw of a wild-type 18.5 dpc embryo (A) stained with alizarin red (bone) and alcian blue (cartilage) shows characteristic features along the proximal-to-distal axis such as the angular process and incisors respectively. The jaw of a mildly affected oto littermate (B) shows distal truncations. Meckel's cartilage was present in the mutant embryo but was lost during dissection of the jaw after staining. Embryos at 9.5 dpc (wild-type in C and oto in D). red arrowheads, distal tip of the branchial arch. The defective oropharynx (op) of severely affected embryos is shown in dark-field views of sagittal section (wild-type in E and oto in F). Rathke's pouch (rp), indicated with a red arrowhead in E is absent in the oto embryo. The foregut endoderm normally fuses with the oral ectoderm to form a seamless tube (E). The foregut is truncated in the oto embryo and the oral cavity does not form (blue arrowheads in F).

Copyright

This image is from Zoltewicz et al., Development 126:5085-5095 (1999), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
C	MGI:1346425 (Hand2)	EMAGE:586
D	MGI:1346425 (Hand2)