Gene Expression Image Detail
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Reference
Figure
ID
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J:42219
Shawlot W, et al., Development. 1999 Nov;126(22):4925-32
2
MGI:1346314
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| Image |
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| Caption | (A) Non-chimeric embryo with normal anterior neural development displaying forebrain (fb), midbrain (mb) and hindbrain (hb). (B) Moderate percentage chimera in which the forebrain region is reduced. An optic placode was not present. (C) Moderate percentage chimera having a small anterior projection bearing a single optic placode (arrowhead). (D) A moderate to high percentage chimera in which the forebrain region is absent. (E) A very high percentage chimera that lacks head structures just anterior to the otic vesicle. (F) Lim1-/- embryo displaying a loss of head structures just anterior to the otic vesicle. All chimeras shown here were generated using Lim1-/- ES cell line 3-21. The arrows in A-F mark the otic vesicle. (G) Expression of Otx2 in an E8.0 wild-type embryo. (H) Expression of Otx2 in a E8.0 Lim1-/--tetraploid (4n) +/+ chimera. (I) Expression of Otx2 in an E8.0 Lim1-/- embryo. The arrows in G-I mark the first branchial arch. | |||||||||
| Copyright | This image is from Shawlot et al., Development 126:4925-4932 (1999), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright. | |||||||||
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Associated Assays |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/30/2025 MGI 6.24 |
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