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Gene Expression Image Detail
Reference
Figure
ID
J:56424 Goodrich LV, et al., Dev Biol. 1999 Jul 15;211(2):323-34
4
MGI:1342052
Image
Caption In A, a section at the level of the hindlimb was hybridized with a mixed probe for Pax3 (purple, dorsal) and Shh (purple, in floor plate (fp) and notochord (nc)) followed by immunohistochemistry for Isl1 (brown). Probe specificity was ascertained by labeling adjacent sections with single probes. In C, a transverse section at the level of forelimb was hybridized with a mixed probe for Pax3 (green) and Nkx2-2 (red). B and D show sections from transgenic animals. The scale bar corresponds to 50 microns in A and 80 microns in C.
Reprinted with permission from Elsevier from doi:10.1006/dbio.1999.9311 Dev Biol 211: 323-34, Goodrich LV; Jung D; Higgins KM; Scott MP, Overexpression of ptc1 inhibits induction of Shh target genes and prevents normal patterning in the neural tube. Copyright 1999
Associated
Assays
Label Assay & Result Details (Gene Symbol) Spatial Mapping
A MGI:1342046 (Isl1) MGI:1342041 (Pax3) MGI:1342043 (Shh)
C MGI:1342070 (Nkx2-2) MGI:1342072 (Pax6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory