Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LRP1	HGNC:6692 (HGNC) 4035 (Entrez Gene) 107770 (OMIM) LRP1 (Alliance of Genome Resources)	Chr12 q13.3	Chr12:57128483-57213361 (+) GRCh38	Alzheimer's disease keratosis pilaris atrophicans myocardial infarction sciatic neuropathy	Q07954 (UniProt | EBI) NM_002332 (RefSeq)
mouse	Lrp1	MGI:96828 (MGI) 16971 (Entrez Gene) Gene Tree Lrp1 (Alliance of Genome Resources)	Chr10 74.52 cM	Chr10:127374030-127457017 (-) GRCm39	Alzheimer's disease cardiomyopathy congenital diaphragmatic hernia gastroschisis omphalocele	ENSMUSG00000040249 (Ensembl Gene Model) ENSMUSP00000044004 (Ensembl) ENSMUST00000049149 (Ensembl)
rat	Lrp1	RGD:1307535 (Rat Genome Database) 299858 (Entrez Gene) Lrp1 (Alliance of Genome Resources)	Chr7 q22			G3V928 (UniProt | EBI) NM_001130490 (RefSeq)
zebrafish	lrp1aa	ZDB-GENE-030131-7889 (Zebrafish Model Organism Database) 563149 (Entrez Gene) lrp1aa (Alliance of Genome Resources)	Chr11			XP_021335354 (RefSeq)
	lrp1ab	ZDB-GENE-030131-7126 (Zebrafish Model Organism Database) 565797 (Entrez Gene) lrp1ab (Alliance of Genome Resources)	Chr23			XP_005162276 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.