Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IFNL1	HGNC:18363 (HGNC) 282618 (Entrez Gene) 607403 (OMIM) IFNL1 (Alliance of Genome Resources)	Chr19 q13.2	Chr19:39296407-39298673 (+) GRCh38	COVID-19 dengue hemorrhagic fever hepatitis C hepatocellular carcinoma	Q8IU54 (UniProt | EBI) NM_172140 (RefSeq)
	IFNL2	HGNC:18364 (HGNC) 282616 (Entrez Gene) 607401 (OMIM) IFNL2 (Alliance of Genome Resources)	Chr19 q13.2	Chr19:39268396-39270188 (+) GRCh38		Q8IZJ0 (UniProt | EBI) NM_172138 (RefSeq)
	IFNL3	HGNC:18365 (HGNC) 282617 (Entrez Gene) 607402 (OMIM) IFNL3 (Alliance of Genome Resources)	Chr19 q13.2	Chr19:39243455-39245250 (-) GRCh38	cryoglobulinemia hepatitis C liver cirrhosis thrombocytopenia	Q8IZI9 (UniProt | EBI) NM_001346937 (RefSeq)
mouse	Ifnl3	MGI:2450574 (MGI) 338374 (Entrez Gene) Gene Tree Ifnl3 (Alliance of Genome Resources)	Chr7 16.81 cM	Chr7:28222261-28223747 (+) GRCm39		ENSMUSG00000060747 (Ensembl Gene Model) ENSMUSP00000077473 (Ensembl) ENSMUST00000078364 (Ensembl)
rat	Ifnl1	RGD:6493686 (Rat Genome Database) 100911249 (Entrez Gene) Ifnl1 (Alliance of Genome Resources)	Chr1			XP_008757509 (RefSeq)
	Ifnl3	RGD:1589046 (Rat Genome Database) 685840 (Entrez Gene) Ifnl3 (Alliance of Genome Resources)	Chr1 q21			XP_006228700 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.