Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AKR1C1	HGNC:384 (HGNC) 1645 (Entrez Gene) 600449 (OMIM) AKR1C1 (Alliance of Genome Resources)	Chr10 p15.1	Chr10:4963253-4983283 (+) GRCh38		Q04828 (UniProt | EBI) NM_001353 (RefSeq)
	AKR1C2	HGNC:385 (HGNC) 1646 (Entrez Gene) 600450 (OMIM) AKR1C2 (Alliance of Genome Resources)	Chr10 p15.1	Chr10:4987775-5018031 (-) GRCh38	46,XY sex reversal 8	P52895 (UniProt | EBI) NM_001354 (RefSeq)
	AKR1C3	HGNC:386 (HGNC) 8644 (Entrez Gene) 603966 (OMIM) AKR1C3 (Alliance of Genome Resources)	Chr10 p15.1	Chr10:5035354-5107686 (+) GRCh38	B-lymphoblastic leukemia/lymphoma leukemia T-cell acute lymphoblastic leukemia	P42330 (UniProt | EBI) NM_001253908 (RefSeq)
	AKR1C4	HGNC:387 (HGNC) 1109 (Entrez Gene) 600451 (OMIM) AKR1C4 (Alliance of Genome Resources)	Chr10 p15.1	Chr10:5195462-5218949 (+) GRCh38	46,XY sex reversal 8	P17516 (UniProt | EBI) NM_001818 (RefSeq)
mouse	Akr1c6	MGI:1933427 (MGI) 83702 (Entrez Gene) Gene Tree Akr1c6 (Alliance of Genome Resources)	Chr13 2.48 cM	Chr13:4484354-4507529 (+) GRCm39		83702 (NCBI Gene Model) P70694 (UniProt | EBI) NM_030611 (RefSeq)
rat	Akr1c1	RGD:1306847 (Rat Genome Database) 307092 (Entrez Gene) Akr1c1 (Alliance of Genome Resources)	Chr17 q12.2			NP_001028869 (RefSeq) NM_001033697 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.