Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAF	HGNC:6776 (HGNC) 4094 (Entrez Gene) 177075 (OMIM) MAF (Alliance of Genome Resources)	Chr16 q23.2	Chr16:79202622-79600737 (-) GRCh38	Ayme-Gripp syndrome cataract cataract 21 multiple types	O75444 (UniProt | EBI) NM_001031804 (RefSeq)
mouse	Maf	MGI:96909 (MGI) 17132 (Entrez Gene) Gene Tree Maf (Alliance of Genome Resources)	Chr8 62.61 cM	Chr8:116429992-116433633 (-) GRCm39	cataract 21 multiple types multiple myeloma	17132 (NCBI Gene Model) P54843 (UniProt | EBI) NM_001025577 (RefSeq)
rat	Maf	RGD:3034 (Rat Genome Database) 54267 (Entrez Gene) Maf (Alliance of Genome Resources)	Chr19 q12			P54844 (UniProt | EBI) NM_019318 (RefSeq)
zebrafish	mafa	ZDB-GENE-010605-2 (Zebrafish Model Organism Database) 114467 (Entrez Gene) mafa (Alliance of Genome Resources)	Chr18			NP_571919 (RefSeq) NM_131844 (RefSeq)
	mafb	ZDB-GENE-141211-38 (Zebrafish Model Organism Database) 100537332 (Entrez Gene) mafb (Alliance of Genome Resources)	Chr25			Q98UK4 (UniProt | EBI) NM_001316669 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.