Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLP2	HGNC:9087 (HGNC) 5355 (Entrez Gene) 300112 (OMIM) PLP2 (Alliance of Genome Resources)	ChrX p11.23	ChrX:49171898-49175235 (+) GRCh38		Q04941 (UniProt | EBI) NM_002668 (RefSeq)
mouse	Plp2	MGI:1298382 (MGI) 18824 (Entrez Gene) Gene Tree Plp2 (Alliance of Genome Resources)	ChrX 3.45 cM	ChrX:7534180-7537629 (-) GRCm39		18824 (NCBI Gene Model) Q9R1Q7 (UniProt | EBI) NM_019755 (RefSeq)
rat	Plp2	RGD:1587363 (Rat Genome Database) 302562 (Entrez Gene) Plp2 (Alliance of Genome Resources)	ChrX q12			Q6P742 (UniProt | EBI) NM_207601 (RefSeq)
zebrafish	plp2a	ZDB-GENE-060312-11 (Zebrafish Model Organism Database) 664695 (Entrez Gene) plp2a (Alliance of Genome Resources)	Chr8			NP_001034924 (RefSeq) NM_001039835 (RefSeq)
	plp2b	ZDB-GENE-030710-11 (Zebrafish Model Organism Database) 798079 (Entrez Gene) plp2b (Alliance of Genome Resources)	Chr8			NP_001154917 (RefSeq) NM_001161445 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.