Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EBF3	HGNC:19087 (HGNC) 253738 (Entrez Gene) 607407 (OMIM) EBF3 (Alliance of Genome Resources)	Chr10 q26.3	Chr10:129835233-129973053 (-) GRCh38	hypotonia, ataxia, and delayed development syndrome	Q9H4W6 (UniProt | EBI) NM_001375389 (RefSeq)
mouse	Ebf3	MGI:894289 (MGI) 13593 (Entrez Gene) Gene Tree Ebf3 (Alliance of Genome Resources)	Chr7 82.26 cM	Chr7:136795402-136916174 (-) GRCm39		ENSMUSG00000010476 (Ensembl Gene Model) ENSMUSP00000147829 (Ensembl) ENSMUST00000210774 (Ensembl)
rat	Ebf3	RGD:1304956 (Rat Genome Database) 361668 (Entrez Gene) Ebf3 (Alliance of Genome Resources)	Chr1 q41			NP_001101976 (RefSeq) NM_001108506 (RefSeq)
zebrafish	ebf3a	ZDB-GENE-070112-292 (Zebrafish Model Organism Database) 567751 (Entrez Gene) ebf3a (Alliance of Genome Resources)	Chr12			NP_001074071 (RefSeq) NM_001080602 (RefSeq)
	ebf3b	ZDB-GENE-131126-3 (Zebrafish Model Organism Database) 556476 (Entrez Gene) ebf3b (Alliance of Genome Resources)	Chr17			XP_009291258 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.