Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	OGDH	HGNC:8124 (HGNC) 4967 (Entrez Gene) 613022 (OMIM) OGDH (Alliance of Genome Resources)	Chr7 p13	Chr7:44606572-44709066 (+) GRCh38	oxoglutarate dehydrogenase deficiency	Q02218 (UniProt | EBI) NM_001165036 (RefSeq)
mouse	Ogdh	MGI:1098267 (MGI) 18293 (Entrez Gene) Gene Tree Ogdh (Alliance of Genome Resources)	Chr11 3.94 cM	Chr11:6241633-6306642 (+) GRCm39		ENSMUSG00000020456 (Ensembl Gene Model) ENSMUSP00000091041 (Ensembl) ENSMUST00000093350 (Ensembl)
rat	Ogdh	RGD:1561359 (Rat Genome Database) 360975 (Entrez Gene) Ogdh (Alliance of Genome Resources)	Chr14 q21			Q5XI78 (UniProt | EBI) NM_001017461 (RefSeq)
zebrafish	ogdha	ZDB-GENE-030131-2143 (Zebrafish Model Organism Database) 564552 (Entrez Gene) ogdha (Alliance of Genome Resources)	Chr8			NP_957073 (RefSeq) NM_200779 (RefSeq)
	ogdhb	ZDB-GENE-090311-8 (Zebrafish Model Organism Database) 797715 (Entrez Gene) ogdhb (Alliance of Genome Resources)	Chr10			XP_021335152 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.