Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACVR1B	HGNC:172 (HGNC) 91 (Entrez Gene) 601300 (OMIM) ACVR1B (Alliance of Genome Resources)	Chr12 q13.13	Chr12:51951699-51997078 (+) GRCh38	lung non-small cell carcinoma lung small cell carcinoma malignant mesothelioma pancreatic cancer stomach cancer	P36896 (UniProt | EBI) NM_001412780 (RefSeq)
mouse	Acvr1b	MGI:1338944 (MGI) 11479 (Entrez Gene) Gene Tree Acvr1b (Alliance of Genome Resources)	Chr15 56.48 cM	Chr15:101071953-101111565 (+) GRCm39		11479 (NCBI Gene Model) Q61271 (UniProt | EBI) NM_007395 (RefSeq)
rat	Acvr1b	RGD:735207 (Rat Genome Database) 29381 (Entrez Gene) Acvr1b (Alliance of Genome Resources)	Chr7 q36			P80202 (UniProt | EBI) NM_199230 (RefSeq)
zebrafish	acvr1ba	ZDB-GENE-980526-527 (Zebrafish Model Organism Database) 30183 (Entrez Gene) acvr1ba (Alliance of Genome Resources)	Chr23			NP_571065 (RefSeq) NM_130990 (RefSeq)
	acvr1bb	ZDB-GENE-131120-9 (Zebrafish Model Organism Database) 559222 (Entrez Gene) acvr1bb (Alliance of Genome Resources)	Chr6			XP_687633 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.