Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NPPB	HGNC:7940 (HGNC) 4879 (Entrez Gene) 600295 (OMIM) NPPB (Alliance of Genome Resources)	Chr1 p36.22	Chr1:11857464-11858945 (-) GRCh38	atherosclerosis hypertension myocardial infarction obesity systolic heart failure	P16860 (UniProt | EBI) NM_002521 (RefSeq)
mouse	Nppb	MGI:97368 (MGI) 18158 (Entrez Gene) Gene Tree Nppb (Alliance of Genome Resources)	Chr4 78.57 cM	Chr4:148070264-148071662 (+) GRCm39		18158 (NCBI Gene Model) P40753 (UniProt | EBI) NM_008726 (RefSeq)
rat	Nppb	RGD:3194 (Rat Genome Database) 25105 (Entrez Gene) Nppb (Alliance of Genome Resources)	Chr5 q36			P13205 (UniProt | EBI) NM_031545 (RefSeq)
zebrafish	nppb	ZDB-GENE-130530-642 (Zebrafish Model Organism Database) 100334610 (Entrez Gene) nppb (Alliance of Genome Resources)	Chr8			NP_001314705 (RefSeq) NM_001327776 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.