Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAST1	HGNC:19034 (HGNC) 22983 (Entrez Gene) 612256 (OMIM) MAST1 (Alliance of Genome Resources)	Chr19 p13.13	Chr19:12833951-12874952 (+) GRCh38	female breast cancer mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations	Q9Y2H9 (UniProt | EBI) NM_014975 (RefSeq)
mouse	Mast1	MGI:1861901 (MGI) 56527 (Entrez Gene) Gene Tree Mast1 (Alliance of Genome Resources)	Chr8 41.32 cM	Chr8:85638532-85663988 (-) GRCm39	mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations	ENSMUSG00000053693 (Ensembl Gene Model) ENSMUSP00000105363 (Ensembl) ENSMUST00000109741 (Ensembl)
rat	MAST1	RGD:631372 (Rat Genome Database) 353118 (Entrez Gene) MAST1 (Alliance of Genome Resources)	Chr19 q11			Q810W7 (UniProt | EBI) NM_181089 (RefSeq)
zebrafish	mast1a	ZDB-GENE-121214-221 (Zebrafish Model Organism Database) 796739 (Entrez Gene) mast1a (Alliance of Genome Resources)	Chr1			XP_009292706 (RefSeq)
	mast1b	ZDB-GENE-131025-2 (Zebrafish Model Organism Database) 796144 (Entrez Gene) mast1b (Alliance of Genome Resources)	Chr3			XP_009297388 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.