Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL21	HGNC:6005 (HGNC) 59067 (Entrez Gene) 605384 (OMIM) IL21 (Alliance of Genome Resources)	Chr4 q27	Chr4:122610108-122621066 (-) GRCh38	asthma common variable immunodeficiency 11 hepatocellular carcinoma systemic lupus erythematosus	Q9HBE4 (UniProt | EBI) NM_021803 (RefSeq)
mouse	Il21	MGI:1890474 (MGI) 60505 (Entrez Gene) Gene Tree Il21 (Alliance of Genome Resources)	Chr3 18.36 cM	Chr3:37276908-37286785 (-) GRCm39		60505 (NCBI Gene Model) Q9ES17 (UniProt | EBI) NM_001291041 (RefSeq)
rat	Il21	RGD:1307384 (Rat Genome Database) 365769 (Entrez Gene) Il21 (Alliance of Genome Resources)	Chr2 q25			A3QPB9 (UniProt | EBI) NM_001108943 (RefSeq)
zebrafish	il21	ZDB-GENE-120510-4 (Zebrafish Model Organism Database) 100150203 (Entrez Gene) il21 (Alliance of Genome Resources)	Chr14			NP_001122046 (RefSeq) NM_001128574 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.