Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SACS	HGNC:10519 (HGNC) 26278 (Entrez Gene) 604490 (OMIM) SACS (Alliance of Genome Resources)	Chr13 q12.12	Chr13:23288689-23433763 (-) GRCh38	Charlevoix-Saguenay spastic ataxia	Q9NZJ4 (UniProt | EBI) NM_014363 (RefSeq)
mouse	Sacs	MGI:1354724 (MGI) 50720 (Entrez Gene) Gene Tree Sacs (Alliance of Genome Resources)	Chr14 32.13 cM	Chr14:61375906-61478144 (+) GRCm39	Charlevoix-Saguenay spastic ataxia	ENSMUSG00000048279 (Ensembl Gene Model) ENSMUSP00000113377 (Ensembl) ENSMUST00000119943 (Ensembl)
rat	Sacs	RGD:1307281 (Rat Genome Database) 305940 (Entrez Gene) Sacs (Alliance of Genome Resources)	Chr15 p12			NP_001414650 (RefSeq) NM_001427721 (RefSeq)
zebrafish	sacs	ZDB-GENE-110411-146 (Zebrafish Model Organism Database) 558150 (Entrez Gene) sacs (Alliance of Genome Resources)	Chr15			XP_009289776 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.