Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ITGA4	HGNC:6140 (HGNC) 3676 (Entrez Gene) 192975 (OMIM) ITGA4 (Alliance of Genome Resources)	Chr2 q31.3	Chr2:181457202-181538940 (+) GRCh38	autism spectrum disorder pancreatic cancer	P13612 (UniProt | EBI) NM_000885 (RefSeq)
mouse	Itga4	MGI:96603 (MGI) 16401 (Entrez Gene) Gene Tree Itga4 (Alliance of Genome Resources)	Chr2 47.38 cM	Chr2:79085770-79163467 (+) GRCm39		ENSMUSG00000027009 (Ensembl Gene Model) ENSMUSP00000099718 (Ensembl) ENSMUST00000099972 (Ensembl)
rat	Itga4	RGD:1593249 (Rat Genome Database) 311144 (Entrez Gene) Itga4 (Alliance of Genome Resources)	Chr3 q24			NP_001101207 (RefSeq) NM_001107737 (RefSeq)
zebrafish	itga4	ZDB-GENE-110411-108 (Zebrafish Model Organism Database) 100331333 (Entrez Gene) itga4 (Alliance of Genome Resources)	Chr9			XP_021334688 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.