Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DOCK1	HGNC:2987 (HGNC) 1793 (Entrez Gene) 601403 (OMIM) DOCK1 (Alliance of Genome Resources)	Chr10 q26.2	Chr10:126905409-127452517 (+) GRCh38		Q14185 (UniProt | EBI) NM_001377554 (RefSeq)
mouse	Dock1	MGI:2429765 (MGI) 330662 (Entrez Gene) Gene Tree Dock1 (Alliance of Genome Resources)	Chr7 79.14 cM	Chr7:134272416-134775376 (+) GRCm39	DiGeorge syndrome tetralogy of Fallot	330662 (NCBI Gene Model) Q8BUR4 (UniProt | EBI) NM_001033420 (RefSeq)
rat	Dock1	RGD:1566072 (Rat Genome Database) 309081 (Entrez Gene) Dock1 (Alliance of Genome Resources)	Chr1 q41			NP_001137330 (RefSeq) NM_001143858 (RefSeq)
zebrafish	dock1	ZDB-GENE-080108-5 (Zebrafish Model Organism Database) 572187 (Entrez Gene) dock1 (Alliance of Genome Resources)	Chr12			NP_001103481 (RefSeq) NM_001110011 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.