Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADAMTSL4	HGNC:19706 (HGNC) 54507 (Entrez Gene) 610113 (OMIM) ADAMTSL4 (Alliance of Genome Resources)	Chr1 q21.2	Chr1:150549369-150560937 (+) GRCh38	autosomal recessive isolated ectopia lentis 2 ectopia lentis with ectopia of pupil	Q6UY14 (UniProt | EBI) NM_019032 (RefSeq)
mouse	Adamtsl4	MGI:2389008 (MGI) 229595 (Entrez Gene) Gene Tree Adamtsl4 (Alliance of Genome Resources)	Chr3 40.74 cM	Chr3:95583511-95595228 (-) GRCm39	autosomal recessive isolated ectopia lentis 2 lens disease	ENSMUSG00000015850 (Ensembl Gene Model) ENSMUSP00000113424 (Ensembl) ENSMUST00000117782 (Ensembl)
rat	Adamtsl4	RGD:1561012 (Rat Genome Database) 310670 (Entrez Gene) Adamtsl4 (Alliance of Genome Resources)	Chr2 q34			Q4FZU4 (UniProt | EBI) NM_001034012 (RefSeq)
zebrafish	adamtsl4	ZDB-GENE-070815-2 (Zebrafish Model Organism Database) 100333903 (Entrez Gene) adamtsl4 (Alliance of Genome Resources)	Chr16			XP_021322468 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.