Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	INPP5K	HGNC:33882 (HGNC) 51763 (Entrez Gene) 607875 (OMIM) INPP5K (Alliance of Genome Resources)	Chr17 p13.3	Chr17:1494577-1516742 (-) GRCh38	congenital muscular dystrophy with cataracts and intellectual disability	Q9BT40 (UniProt | EBI) NM_016532 (RefSeq)
mouse	Inpp5k	MGI:1194899 (MGI) 19062 (Entrez Gene) Gene Tree Inpp5k (Alliance of Genome Resources)	Chr11 45.92 cM	Chr11:75521814-75539697 (+) GRCm39		ENSMUSG00000006127 (Ensembl Gene Model) ENSMUSP00000006286 (Ensembl) ENSMUST00000006286 (Ensembl)
rat	Inpp5k	RGD:1359130 (Rat Genome Database) 287533 (Entrez Gene) Inpp5k (Alliance of Genome Resources)	Chr10 q24			NP_001013881 (RefSeq) NM_001013859 (RefSeq)
zebrafish	inpp5ka	ZDB-GENE-070410-101 (Zebrafish Model Organism Database) 100037338 (Entrez Gene) inpp5ka (Alliance of Genome Resources)	Chr15			NP_001082962 (RefSeq) NM_001089493 (RefSeq)
	inpp5kb	ZDB-GENE-100408-3 (Zebrafish Model Organism Database) 566188 (Entrez Gene) inpp5kb (Alliance of Genome Resources)	Chr10			XP_021335021 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.