Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SCN3A	HGNC:10590 (HGNC) 6328 (Entrez Gene) 182391 (OMIM) SCN3A (Alliance of Genome Resources)	Chr2 q24.3	Chr2:165087526-165204050 (-) GRCh38	developmental and epileptic encephalopathy 62 focal epilepsy	Q9NY46 (UniProt | EBI) NM_001081676 (RefSeq)
mouse	Scn3a	MGI:98249 (MGI) 20269 (Entrez Gene) Gene Tree Scn3a (Alliance of Genome Resources)	Chr2 38.55 cM	Chr2:65288607-65397971 (-) GRCm39		ENSMUSG00000057182 (Ensembl Gene Model) ENSMUSP00000097647 (Ensembl) ENSMUST00000100069 (Ensembl)
rat	Scn3a	RGD:3635 (Rat Genome Database) 497770 (Entrez Gene) Scn3a (Alliance of Genome Resources)	Chr3 q21			P08104 (UniProt | EBI) NM_013119 (RefSeq)
zebrafish	scn1lab	ZDB-GENE-060906-1 (Zebrafish Model Organism Database) 559447 (Entrez Gene) scn1lab (Alliance of Genome Resources)	Chr6			NP_001038360 (RefSeq) NM_001044895 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.