Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ISM2	HGNC:23176 (HGNC) 145501 (Entrez Gene) 612684 (OMIM) ISM2 (Alliance of Genome Resources)	Chr14 q24.3	Chr14:77474394-77498816 (-) GRCh38		Q6H9L7 (UniProt | EBI) NM_199265 (RefSeq)
mouse	Ism2	MGI:2685110 (MGI) 217738 (Entrez Gene) Gene Tree Ism2 (Alliance of Genome Resources)	Chr12 41.49 cM	Chr12:87325412-87346479 (-) GRCm39		ENSMUSG00000050671 (Ensembl Gene Model) ENSMUSP00000117108 (Ensembl) ENSMUST00000125733 (Ensembl)
rat	Ism2	RGD:1589343 (Rat Genome Database) 681936 (Entrez Gene) Ism2 (Alliance of Genome Resources)	Chr6			XP_063118755 (RefSeq)
zebrafish	ism2a	ZDB-GENE-130530-972 (Zebrafish Model Organism Database) 100535376 (Entrez Gene) ism2a (Alliance of Genome Resources)	Chr17			XP_003200388 (RefSeq)
	ism2b	ZDB-GENE-050523-4 (Zebrafish Model Organism Database) 553163 (Entrez Gene) ism2b (Alliance of Genome Resources)	Chr20			Q58T08 (UniProt | EBI) NM_001020509 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.