Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FGD4	HGNC:19125 (HGNC) 121512 (Entrez Gene) 611104 (OMIM) FGD4 (Alliance of Genome Resources)	Chr12 p11.21	Chr12:32399558-32646050 (+) GRCh38	Charcot-Marie-Tooth disease type 4H	Q96M96 (UniProt | EBI) NM_001384130 (RefSeq)
mouse	Fgd4	MGI:2183747 (MGI) 224014 (Entrez Gene) Gene Tree Fgd4 (Alliance of Genome Resources)	Chr16 10.18 cM	Chr16:16234774-16418400 (-) GRCm39	Charcot-Marie-Tooth disease type 4H	224014 (NCBI Gene Model) Q91ZT5 (UniProt | EBI) NM_001301817 (RefSeq)
rat	Fgd4	RGD:708357 (Rat Genome Database) 246174 (Entrez Gene) Fgd4 (Alliance of Genome Resources)	Chr11 q23			O88387 (UniProt | EBI) NM_001415054 (RefSeq)
zebrafish	fgd4a	ZDB-GENE-050420-347 (Zebrafish Model Organism Database) 556216 (Entrez Gene) fgd4a (Alliance of Genome Resources)	Chr18			NP_001171404 (RefSeq) NM_001177933 (RefSeq)
	fgd4b	ZDB-GENE-110421-6 (Zebrafish Model Organism Database) 793364 (Entrez Gene) fgd4b (Alliance of Genome Resources)	Chr4			XP_021330870 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.