Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	VPS33B	HGNC:12712 (HGNC) 26276 (Entrez Gene) 608552 (OMIM) VPS33B (Alliance of Genome Resources)	Chr15 q26.1	Chr15:90998416-91022621 (-) GRCh38	arthrogryposis multiplex congenita arthrogryposis, renal dysfunction, and cholestasis 1 cholestasis kidney disease progressive familial intrahepatic cholestasis	Q9H267 (UniProt | EBI) NM_001289149 (RefSeq)
mouse	Vps33b	MGI:2446237 (MGI) 233405 (Entrez Gene) Gene Tree Vps33b (Alliance of Genome Resources)	Chr7 45.59 cM	Chr7:79919369-79941327 (+) GRCm39	ARC syndrome	233405 (NCBI Gene Model) P59016 (UniProt | EBI) NM_001420428 (RefSeq)
rat	Vps33b	RGD:620644 (Rat Genome Database) 64060 (Entrez Gene) Vps33b (Alliance of Genome Resources)	Chr1 q31			Q63616 (UniProt | EBI) NM_022286 (RefSeq)
zebrafish	vps33b	ZDB-GENE-050327-73 (Zebrafish Model Organism Database) 541534 (Entrez Gene) vps33b (Alliance of Genome Resources)	Chr7			Q58EN8 (UniProt | EBI) NM_001014348 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.