Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CASR	HGNC:1514 (HGNC) 846 (Entrez Gene) 601199 (OMIM) CASR (Alliance of Genome Resources)	Chr3 q13.33-q21.1	Chr3:122183668-122291629 (+) GRCh38	autosomal dominant hypocalcemia autosomal dominant hypocalcemia 1 calcium oxalate nephrolithiasis familial hypocalciuric hypercalcemia 1 hypercalcemia hyperparathyroidism idiopathic generalized epilepsy 8 intellectual disability nephrolithiasis secondary hyperparathyroidism	P41180 (UniProt | EBI) NM_001178065 (RefSeq)
mouse	Casr	MGI:1351351 (MGI) 12374 (Entrez Gene) Gene Tree Casr (Alliance of Genome Resources)	Chr16 25.57 cM	Chr16:36314058-36382503 (-) GRCm39	autosomal dominant hypocalcemia 1 familial hypocalciuric hypercalcemia 1 hyperparathyroidism	ENSMUSG00000051980 (Ensembl Gene Model) ENSMUSP00000133500 (Ensembl) ENSMUST00000172826 (Ensembl)
rat	Casr	RGD:2277 (Rat Genome Database) 24247 (Entrez Gene) Casr (Alliance of Genome Resources)	Chr11 q22			P48442 (UniProt | EBI) NM_001309638 (RefSeq)
zebrafish	casr	ZDB-GENE-050119-8 (Zebrafish Model Organism Database) 560607 (Entrez Gene) casr (Alliance of Genome Resources)	Chr5			NP_001338594 (RefSeq) NM_001351665 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.