Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	POLR3K	HGNC:14121 (HGNC) 51728 (Entrez Gene) 606007 (OMIM) POLR3K (Alliance of Genome Resources)	Chr16 p13.3	Chr16:46407-53608 (-) GRCh38	hypomyelinating leukodystrophy 21	Q9Y2Y1 (UniProt | EBI) NM_016310 (RefSeq)
mouse	Polr3k	MGI:1914255 (MGI) 67005 (Entrez Gene) Gene Tree Polr3k (Alliance of Genome Resources)	Chr2 103.82 cM	Chr2:181506153-181512623 (+) GRCm39		67005 (NCBI Gene Model) Q9CQZ7 (UniProt | EBI) NM_025901 (RefSeq)
rat	Polr3k	RGD:1587294 (Rat Genome Database) 366277 (Entrez Gene) Polr3k (Alliance of Genome Resources)	Chr3 q43			NP_001014281 (RefSeq) NM_001014259 (RefSeq)
zebrafish	polr3k	ZDB-GENE-040718-291 (Zebrafish Model Organism Database) 436826 (Entrez Gene) polr3k (Alliance of Genome Resources)	Chr3			NP_001002553 (RefSeq) NM_001002553 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.