Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF2B3	HGNC:3259 (HGNC) 8891 (Entrez Gene) 606273 (OMIM) EIF2B3 (Alliance of Genome Resources)	Chr1 p34.1	Chr1:44850522-44986722 (-) GRCh38	leukoencephalopathy with vanishing white matter 3	Q9NR50 (UniProt | EBI) NM_001261418 (RefSeq)
mouse	Eif2b3	MGI:1313286 (MGI) 108067 (Entrez Gene) Gene Tree Eif2b3 (Alliance of Genome Resources)	Chr4 53.41 cM	Chr4:116876559-116944049 (+) GRCm39		108067 (NCBI Gene Model) NP_001104747 (RefSeq) NM_175135 (RefSeq)
rat	Eif2b3	RGD:620821 (Rat Genome Database) 171145 (Entrez Gene) Eif2b3 (Alliance of Genome Resources)	Chr5 q36			P70541 (UniProt | EBI) NM_133609 (RefSeq)
zebrafish	eif2b3	ZDB-GENE-040426-1039 (Zebrafish Model Organism Database) 394049 (Entrez Gene) eif2b3 (Alliance of Genome Resources)	Chr2			NP_957368 (RefSeq) NM_201074 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.